Skip to main content
Premium Trial:

Request an Annual Quote

Gotcha!: Jul 6, 2012

Premium

Cornell University's Brian Kirby and his colleagues reported on their development of a 'sticky' silicon chip known as geometrically enhanced differential immunocapture, or GEDI, in PLoS One in April. Now, Kirby tells the Cornell Chronicle, the researchers are applying this new cell-capture device to trap circulating tumor cells in blood samples from patients with metastatic cancers.

"Most cancer cells are bigger and more rigid than normal cells, so it's about tricking these cancer cells into colliding with the sticky walls," Kirby tells the Cornell Chronicle. The paper adds that the GEDI device is slated to go to clinical trial this year, and the Kirby and his colleagues "are actively working on detectors for breast, ovarian and pancreatic cancers."

HT: Fierce Health IT

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.