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Gentronix to Provide GSK with Genotoxicity Assay

Feb 24, 2009

NEW YORK (GenomeWeb News) – Gentronix today said that it will provide GlaxoSmithKline with its genotoxicity detection assay, GreenScreen HC, for use in the drug firm's safety evaluation studies.

According to Manchester, UK-based Gentronix, GreenScreen HC is the first human cell-based assay technology that combines high sensitivity for detecting genotoxic chemicals with high specificity for reducing false positive results. The assay uses green fluorescent protein to detect GADD-45a up regulation, which is a key indicator of DNA damage, said Gentronix.

John Nicholson, chairman and CEO of Gentronix, said that the firm had previously worked with GSK on early validation of the technology.

Financial terms of the alliance were not disclosed.

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