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Gentris Licenses LGC s CYP450 Polymorphism for Use in Genotyping Service

NEW YORK, June 7 (GenomeWeb News) - Gentris has taken a non-exclusive license from LGC for a common drug-metabolism polymorphism, the companies said today.


According to the terms of the agreement, Gentris gains the rights to make, use, and sell diagnostic products and services that rely on LGC's CYP450 2D6*4 polymorphism.


Gentris plans to use the polymorphism in its genotyping service, CEO Michael Murphy said.


LGC is the exclusive licensor of the polymorphism.


The *4 polymorphism is the most common CYP450 2D6 polymorphism in Caucasians, and the 2D6 gene itself is believed to be involved in the metabolism of about 30 percent of approved drugs.

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