GenTel BioSurfaces to Market and Sell Kreatech s ULS Labeling Kits

NEW YORK, Aug. 16 (GenomeWeb News) - GenTel BioSurfaces will market and sell ULS labeling reagent kits made by Kreatech Biotechnology, the companies said today.

The kits, which will be sold under the brand name Pandeia, are validated for use on GenTel's PATH protein microarray platform. They will be launched during the Chips to Hits conference in Bostonon Sept. 12, the company said.

For one- or two-color fluorescent profiling of the relative abundance of proteins using single capture antibody arrays, each protein sample is labeled with either ULS-biotin or ULS-fluorescein, and probed against the antibody microarray, the companies said in a statement.

The bound labeled proteins are detected using fluorescent Dy dyes made by Dyomics using either a streptavidin-Dy647 conjugate or an anti-fluorescein antibody-Dy547 conjugate. The processed microarray is scanned on a standard two-color fluorescent scanner. Kreatech, which holds a license from Dyomics, has sub-licensed the rights to market and sell Dyomics' dye conjugates to GenTel.

GenTel's PATH protein array surface technology consists of an ultra-thin nitrocellulose film used for multiplex immunoassays. ULS labels multiple amino acids, the companies said. The use of the ULS labeling system "further minimizes background noise using indirect fluorescence detection."