NEW YORK, May 25 (GenomeWeb News) - Researchers at Genpathway and Baylor College of Medicine have used Genpathway's transcription analysis technology to identify genes involved in breast cancer, the San Diego-based company said today.
The scientists used Genpathways's Factor Path assay, one of several transcription-based assays that measure transcription directly, rather than by RNA levels, to identify genes regulated by a protein overexpressed in breast cancer.
The assay identifies genomic DNA sequences that are functionally associated with a particular transcription factor or coregulator and quantifies the binding level of each factor across the genome. Another Genpathway assay, TranscriptionPath, showed that the genes identified are biologically relevant.
The study was published earlier this year in PNAS.