Skip to main content
Premium Trial:

Request an Annual Quote

Genome Therapeutics and EraGen to Combine Databases

NEW YORK, March 5  - Genome Therapeutics and EraGen Biosciences of Alachua, Fla., will collaborate to combine and co-market EraGen's MasterCatalog bioinformatics platform with Genome Therapeutics' Pathogenome database of microbial genomic sequences, the companies said Monday.

The PathoGenome database offers functionally annotated sequence information on over 30 microbial pathogens, including Staphylococcus , Pseudomonas , Streptococcus , Enterococcus , Acinetobacter , Aspergillus , Bacteroides , Enterobacter , Klebsiella , and Candida  species.

MasterCatalog combines data mining and analysis tools with a sequence library of 50,000 protein families and protein families. The companies will fold the Pathogenome sequence information into the MasterCatalog database.

"Combining the Pathogenome database with MasterCatalog's bioinformatics platform increases the discovery potential for both products," said Gary Alianell, COO of EraGen, in a statement. "MasterCatalog's pre-computed protein analyses will streamline the datamining process, allowing biologists to work directly with Pathogenome's data without the aid of a bioinformatics expert."

GenomeTherapeutics offers Pathogenome on a pay-per-use basis through Compugen's search engine The fee is based on the amount of information accessed per search.   

The database is also available by subscription, and its subscribers so far include Aventis, Bayer, bioMerieux, Bristol-Myers Squibb, and Schering-Plough.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.