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Genome Sequence of Deep Sea Bacterium Reveals Adapations to Life Under High Pressure

NEW YORK, March 7 (GenomeWeb News) - Scientists in Italyand the UShave sequenced the genome of Photobacterium profundum, a bacterium that lives in the deep sea under high pressure.


The 6.4-megabase genome is split up into two circular chromosomes and one plasmid. The scientists found several metabolic, regulatory, and structural adaptations to deep-sea conditions.


The scientists, from the Universityof Padovain Italyand the Scripps Institution of Oceanography at the Universityof California San Diego, published their findings in last week's Science.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.