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Genome of Parasite C. Parvum Sequenced

NEW YORK, March 29 (GenomeWeb News) - Researchers led by the University of Minnesota have sequenced the genome of Cryptosporidium parvum, a parasite in humans and animals, and published their findings on Thursday.


The scientists reported finding several novel classes of cell-surface and secreted proteins with a potential role in pathogenesis. They also found enzymes that are very similar to counterparts in bacteria and plants, making them potential drug targets.


C. parvum causes diarrhea in humans and animals and can be fatal in immunocompromised patients.


The study appeared in the March 25 issue of Sciencexpress, the online version of Science.

The sequencing project was part of the University of Minnesota's "microbial pathogenomics" research program that aims to sequence the genomes of a wide range of human and animal pathogens.