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Genome Library: DNA from A to Z and DNA Sequencing: Optimizing the Process and Analysis


DNA from A to Z
By Daniel Farkas

This reference book is first and foremost a book for the layman — or a scientist unfamiliar with molecular biology. Entries, arranged alphabetically, describe the basic terms of DNA sequencing and analysis, with particular attention paid to molecular diagnostics. The book may also, the author notes, help familiarize biologists with language suitable for describing their work to non-scientists curious enough to ask.

DNA Sequencing: Optimizing the Process and Analysis
By Jan Kieleczawa

A thorough, technical review of various phases of sequencing from cloning to reagents to LIMS, this book is not for a general audience. Thoughtful foreword by Elaine Mardis, with chapters by Kieleczawa as well as a range of biotech and pharma researchers.

— JM and MS


The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.