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Genome Library


Short Protocols in Human Genetics

Edited by: Nicholas Dracopoli, Jonathan Haines, Bruce Korf, Cynthia Morton, Anthony Rosenzweig, Christine Seidman, JG Seidman, and Douglas Smith

Published in November 2004, Short Protocols serves as a companion to Current Protocols in Human Genetics, also published by Wiley. This text provides abbreviated but precise lab methods ranging from basic science to clinical research. General topics include genetic mapping, genotyping, finding and identifying candidate genes, transcriptional profiling, and gene therapy, among others. The protocols are written clearly and with attention to detail; they cover both the old standbys as well as newer techniques, such as comparative genomic hybridization. — MS


Forensic DNA Typing
Biology, Technology, and Genetics of STR Markers, 2nd Edition

Written by: John M. Butler

Geared toward the forensic scientist, legal professional, and college student, Forensic DNA Typing offers a comprehensive look at the field of DNA applied to criminal forensics today, as well as the trends shaping the field’s development in the future. The author, a forensic scientist by training who helped develop the Short Tandem Repeat Internet Database while a postdoc at NIST, details the biology, technology, and genetics required to perform STR-based forensic science, and delves into new technology employing SNPs and Y chromosome testing. New additions to the second edition also include new DNA extraction procedures, real-time PCR for DNA quantification, and a discussion of statistical issues associated with data analysis and interpretation. — JSM


The Scan

Not as High as Hoped

The Associated Press says initial results from a trial of CureVac's SARS-CoV-2 vaccine suggests low effectiveness in preventing COVID-19.

Finding Freshwater DNA

A new research project plans to use eDNA sampling to analyze freshwater rivers across the world, the Guardian reports.

Rise in Payments

Kaiser Health News investigates the rise of payments made by medical device companies to surgeons that could be in violation of anti-kickback laws.

Nature Papers Present Ginkgo Biloba Genome Assembly, Collection of Polygenic Indexes, More

In Nature this week: a nearly complete Ginkgo biloba genome assembly, polygenic indexes for dozens of phenotypes, and more.