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Genes with Liquid Lasers


Researchers at the University of Michigan are developing a way to detect gene mutations linked to cancer using a liquid laser, says the university's news service. Instead of using dyes or other biological tags to mark mutated genes — a technique that is less than perfect as the tags can bind to normal DNA and cause researchers to misinterpret the signal — the UMich research team developed a system based on laser emission "for differentiating a target DNA strand from strands that contain single base mismatches," the school adds. "Laser emission is used to amplify the small difference in signals that are generated by the different strands after they bind with a molecular beacon." This system renders mutated DNA hundreds of times brighter than normal DNA, allowing the researchers to filter out unwanted signals.

The Scan

Should've Been Spotted Sooner

Scientists tell the Guardian that SARS-CoV-2 testing issues at a UK lab should have been noticed earlier.

For Martian Fuel

Researchers have outlined a plan to produce rocket fuel on Mars that uses a combination of sunlight, carbon dioxide, frozen water, cyanobacteria, and engineered E. coli, according to Gizmodo.

To Boost Rapid Testing

The Washington Post writes that new US programs aim to boost the availability of rapid at-home SARS-CoV-2 tests.

PNAS Papers on Strawberry Evolution, Cell Cycle Regulators, False-Positive Triplex Gene Editing

In PNAS this week: strawberry pan-genome, cell cycle-related roles for MDM2 and MDMX, and more.