Matthew Trunnell washed into bioinformatics quite by accident. Trained as a physicist, Trunnell kicked off his career in oceanography, studying circulation patterns of water. Those studies required large-scale simulations, which lured him into the realm of computing infrastructure, and after a brief stint as a Unix-based consultant, he wound up at Genome Therapeutics. “It was my first exposure to bioinformatics,” he recalls. “I was enthralled with the science and with the problems in the field.”

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