If the Holy Grail of systems biology — or at least one of the grails — is to computationally simulate the behavior of cells, then scientists are going to have to start their crusade by assembling the little clues. In the March 25 issue of Science, researchers took another measured step forward in the attempt to begin understanding how individual cells behave by reporting on their experiments with gene regulation networks.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.