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Funding Update: May 24, 2011

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Microarray-Related NIH Grants, Jan. 1 – May 24, 2011, Part I of II

Modeling, Synthesis, and Biological Evaluation of Potential RXT Selective Agonist
Principal investigator: Carl Wagner
Organization: Arizona State University Tempe
Project start date: Jan. 1, 2011
Project end date: Dec. 31, 2013
NIH institute: NCI
FY 2011 funding amount: $457,500


MicroRNAs as Novel Biomarkers for Management of Breast Cancer
Principal investigator: Lorenzo Sempere
Organization: Dartmouth College
Project start date: Jan. 1, 2011
Project end date: Dec. 31, 2012
NIH institute: NCI
FY 2011 funding amount: $206,190


Global Analysis of Sumo Substrate Selection Using Protein Microarray Technology
Principal investigator: Ijeoma Uzoma
Organization: Johns Hopkins University
Project start date: Jan. 1, 2011
Project end date: Dec. 31, 2013
NIH institute: NIGMS
FY 2011 funding amount: $48,100


The Role of Notch in Behavioral Plasticity
Principal investigator: Gary Struhl
Organization: Columbia University Health Sciences
Project start date: Jan. 1, 2011
Project end date: Dec. 31, 2014
NIH institute: NIGMS
FY 2011 funding amount: $310,836


Randomized Comparison of Ductal Preservation Solutions for Improving Quantity
Principal investigator: Shinichi Matsumoto
Organization: Baylor Research Institute
Project start date: Jan. 1, 2011
Project end date: Dec. 31, 2012
NIH institute: NIDDKD
FY 2011 funding amount: $235,200


Epigenetics of Sex Differences in Brain and Behavior
Principal investigator: Bridget Nugent
Organization: University of Maryland Baltimore
Project start date: Jan. 7, 2011
Project end date: Jan. 6, 2013
NIH institute: NINDS
FY 2011 funding amount: $30,755


Genetic Characterization of Long-term Memory in Caenorhabditis elegans
Principal investigator: Rachel Kaletsky
Organization: Princeton University
Project start date: Jan. 1, 2011
Project end date: Dec. 31, 2013
NIH institute: NINDS
FY 2011 funding amount: $48,398


Regulation of B-Catenin by RPTPB/Z in Fetal Human Glial Progenitors
Principal investigator: Crystal McClain
Organization: University of Rochester
Project start date: Feb. 1, 2011
Project end date: Jan. 31, 2013
NIH institute: NINDS
FY 2011 funding amount: $35,400


Microarray-based Biomarkers in Juvenile Idiopathic Arthritis
Principal investigator: James Jarvis
Organization: University of Oklahoma Health Sciences Center
Project start date: Feb. 1, 2011
Project end date: Jan. 31, 2016
NIH institute: NIAMSD
FY 2011 funding amount: $535,410


Chemotherapy-induced Painful Neuropathy: Target Genes and Pathway Discovery
Principal investigator: Lauren Ta
Organization: Mayo Clinic
Project start date: Feb. 15, 2011
Project end date: Jan. 13, 2013
NIH institute: NIDCR
FY 2011 funding amount: $118,275

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Mechanisms and Functional Consequences of Reovirus Innate Immune Activation
Principal investigator: Geoffrey Holm
Organization: Colgate University
Project start date: Feb. 15, 2011
Project end date: March 31, 2014
NIH institute: NIAID
FY 2011 funding amount: $370,561


Transcription Factor Cross-Talk in Developmental Toxicity
Principal investigator: Larissa Williams
Organization: Woods Hole Oceanographic Institute
Project start date: March 1, 2011
Project end date: Feb. 28, 2014
NIH institute: NIEHS
FY 2011 funding amount: $48,290


Identification of a Novel Signaling Network in Porphromonas gingivalis
Principal investigator: Hua Xie
Organization: Meharry Medical College
Project start date: March 1, 2011
Project end date: Feb. 28, 2013
NIH institute: NIDCR
FY 2011 funding amount: $236,125


Mosquito Larval Immunity and Its Impact on Gut Microbiota and Malaria Competence
Principal investigator: Jiannong Xu
Organization: New Mexico State University Las Cruces
Project start date: March 1, 2011
Project end date: Feb. 28, 2014
NIH institute: NIGMS
FY 2011 funding amount: $137,800


The Influence of the ZXDC Protein on Myelopoiesis
Principal investigator: Joseph Fontes
Organization: University of Kansas Medical Center
Project start date: March 1, 2011
Project end date: Feb. 28, 2013
NIH institute: NIAID
FY 2011 funding amount: $75,000


Psychosocial Stress Interactions with Electrophysiology and Brain Aging
Principal investigator: Eric Blalock
Organization: University of Kentucky
Project start date: March 1, 2011
Project end date: Feb. 29, 2016
NIH institute: NIA
FY 2011 funding amount: $303,566


Statistical Methods for Normalizing Microarrays in Cancer Biomarker Studies
Principal investigator: Li-Xuan Qin
Organization: Sloan-Kettering Institute for Cancer Research
Project start date: March 1, 2011
Project end date: Feb. 28, 2015
NIH institute: NCI
FY 2011 funding amount: $723,757

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.