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Former NimbleGen CEO to Head Sangamo Bio, Spotfire Hires Tony Colangelo and Olle Landstrom, ABI s Deborah Smeltzer Lands at Dynavax, Guava Hires BD s Philip Vorwald, and Others

Nick Colangelo has become senior vice president of corporate development and operations at Oscient Pharmaceuticals, the Waltham, Mass.-based company said yesterday. He comes to Oscient from Eli Lilly, where he was a managing director of Lilly Ventures. Colangelo holds a law degree from the Duke University School of Law and a bachelor's degree from the State University of New York at Buffalo.

Tina Nova has joined the board of directors of Heska, a veterinary diagnostic products manufacturer, the company said last week. Nova is president, CEO, director, and co-founder of Genoptix. She served as president and COO of Nanogen from 1994 to 2000. Nova holds a PhD in biochemistry from the Universityof California, Riversideand a BSc in biological sciences from the Universityof California, Irvine.

David Ichikawa has become senior vice president for business development at Sangamo BioSciences, the Point Richmond, Calif.-based company said yesterday. Most recently, he was chief business officer of Sagres Discovery. Prior to that, he held several positions with Chiron. Ichikawaholds an MBA from the University of California at Berkeley and a BS from the University of California at Davis.

Michael Treble has become CEO of the Ibis program of Isis Pharmaceuticals, the company said yesterday. Ibis plans to develop a biosensor to identify infectious organisms. Prior to joining Isis, he founded Tienta Sciences and SonoPlot. Before that, he was president and CEO of NimbleGen Systems. He was also executive vice president, COO, and director of Third Wave Technologies. Treble holds an MBA from the Universityof Buffaloand a BS from CanisiusCollege, also in Buffalo.


In addition, Richard DiMarchi has joined the board of directors of Isis, the company said last month.  He is a professor of biomolecular science at IndianaUniversity, Bloomington. Prior to this, he led the biotechnology group at Eli Lilly Research Laboratories. He is also a partner at Twilight Venture Fund, and is a former member of the board of the Biotechnology Industry Organization. DiMarchi holds a PhD from IndianaUniversity, and a BS from Florida Atlantic University.

Bryan Koontz has joined Tripos as vice president of corporate development for discovery informatics as part of the recent acquisition of Optive Research by Tripos, the St. Louis-based company said today. He is the former CEO of Optive. In addition, several scientists and developers from Optive have joined Tripos's Discovery Informatics business and will continue to work out of Austin, Texas.

Tony Colangelo has become vice president of North American sales and Olle Landström vice president of engineering for Spotfire, the Somerville, Mass.-based company said today. The company has also added several new field representatives in all regions. Colangelo joins Spotfire from Bristol Technologies, where he led the field sales team. Landström, who will be based in Göteborg, Sweden, comes to Spotfire from IAR Systems in Sweden, where he was CTO.

Deborah Smeltzer has become CFO and vice president for operations of Dynavax, the Berkeley, Calif.-based company said today. She joins Dynavax from Applied Biosystems, where she was vice president and general manager of the company's genetic analysis business. Prior to that, she was CFO and vice president of Genset, a French genomics company. Smeltzer holds an MBA from the Stanford University Graduate School of Business and an MS in medical microbiology from the Universityof California, Irvine.

Allen Ruzycki has joined Phyton Biotech, a subsidiary of Fort Worth, Texas-based DFB Pharmaceuticals, as director of finance and administration, the company said last week. Most recently, he was acting director of finance for an unnamed privately held company, Phyton said. He has also been employed by Nabisco, Fisher Scientific, Poly Chrome, and BASF Corporation. Ruzycki holds a BA in finance from DrexelUniversityand an MBA in finance from Fairleigh Dickinson University.

Philip Vorwald has become vice president of worldwide sales for Guava Technologies, the Hayward, Calif.-based company said on Monday. Recently, he was managing director of Delphi Medical Systems. Prior to that, he held several positions at Becton Dickinson Biosciences. Vorwald holds an MS from the Medical College of Virginia and a BS from the CatholicUniversityin Washington, DC.

Frank Baldino has joined the board of directors of Pennsylvania Bio, the organization said last week. He is the CEO, chairman, and founder of Cephalon. Baldino holds a PhD in pharmacology from TempleUniversity.

Merrilyn Datta has become the new director of RNAi in the functional genomics business segment of Invitrogen, GenomeWeb News has learned. She replaces Nikki Zahl, who has become director of genomics at Invitrogen. She was previously marketing manager for RNAi at the company, and before that marketing manager for cloning and gene expression. Datta holds a PhD from HarvardUniversity, and a BS from EmoryUniversity.

EMBL has established a Bioinformatics Advisory Committee. Members of the committee include Søren Brunak, chairman of the Technical University of Denmark; John Sulston of the Wellcome Trust Sanger Institute; Anna Tramontano of the University of Rome "La Sapienza;" Martin Vingron of the Max Planck Institute for Molecular Genetics; and Gunnar von Heijne of Stockholm University.

The Scan

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Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.