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Exelixis to Use Invitrogen s Assays for Drug Discovery

NEW YORK, Aug 12 (GenomeWeb News) - Invitrogen said today that it will provide Exelixis with validated high-throughput screening assays for drug discovery in single live cells, which Exelixis will use for lead discovery and optimization.

 

Carlsbad, Calif.-based Invitrogen said that its Drug Discovery Solutions group would provide Exelixis with its GeneBlazer and Voltage Sensor Probe technologies for compound screening. The GeneBlazer cell-based beta-lactamase system combines molecular and cellular biology with a fluorescence resonance energy transfer-based detection method for high-throughput screening experiments.

 

Invitrogen recently announced that the GeneBlazer and Voltage Sensor Probe technologies would be available for purchase by researchers without a licensing agreement.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

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Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.