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European Consortium Awards $29.5M for 16 Projects Employing Systems Biology

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) — A European consortium that promotes the convergence of life science with information technology and systems biology has awarded funding for 16 research projects totaling €24 million ($29.5 million).

ERASYSBIO+ has agreed to fund systems biology projects involving a total 85 research groups from 14 countries. Those partner countries provided a total €18.5 million of the funding, with the remaining €5.5 million coming from the European Union.

The 16 were chosen from among 51 full proposals for transnational research projects, according to the consortium.

ERASYSBIO+ consists of 16 national and regional science ministries from 13 countries — Austria, Belgium, Finland, France, Germany, Israel, Luxembourg, the Netherlands, Norway, Russia, Slovenia, Spain, and the UK. Non-partner countries with groups participating in the transnational research projects are the US, Iceland, Italy, and South Africa.

The programs approved for funding by the consortium include:

FRIM - FRuit Integrative Modelling

LINCONET - Modelling the Gene Regulatory Network underlying Lineage Commitment in Human Mesenchymal Stem Cells: Identification of Drug Targets for the Anabolic Treatment of Degenerative Disorders

BioModUE_PTL - Biophysical Modelling of the Uterine Electromyogram for understanding and preventing PreTerm Labor.

Zebrain - Understanding decision making from the dynamics of large neural populations in behaving zebrafish.

SYNERGY - Systems approach to gene regulation biology through nuclear receptors.

SynProt - A Systems Biological Approach to Elucidate Local Protein Synthesis Code in Plasticity and Memory.

LymphoSys - Signalling pathways and gene regulatory networks responsible for Th17 cell differentiation.

SHIPREC – Salmonella Host Interactions PRoject European Consortium. Living with uninvited guests comparing plant and animal responses to endocytic invasions.

ModHeart - Modelling the genetic network controlling heart development using the model organism Drosophila melanogaster.

C5Sys - Circadian and cell cycle clock systems in cancer.

iSAM - Integrative Systems Analysis of the Shoot Apical Meristem.

livSYSiPS - The systems biology of network stress based on data generated from in vitro differentiated hepatocytes derived from patient-specific human iPS cells.

EpiGenSys - System Biological Determination of the Epigenomic Structure-Function Relation.

GRAPPLE - Iterative modelling of gene regulatory interactions underlying stress, disease and ageing in C. elegans.

ApoNET - Systems Analysis of TNF and TRAIL Signalling Pathways in Hepatocytes

TB-HOST-NET - Integration of computational modelling with transcription and gene essentiality profiling of both MTB bacillus and infected human dendritic cells and macrophages to understand molecular interaction networks involved in the host-pathogen cross-talk

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