Skip to main content
Premium Trial:

Request an Annual Quote

European AIDS Research Center to Test CombiMatrix siRNA against HIV

NEW YORK, June 30 - CombiMatrix is collaborating with the Retrovirology Laboratory irsiCaixa, an AIDS research center based in Barcelona, to test the efficacy of its pooled siRNA compounds against Human Immunodeficiency Virus, Type-1, the company said today.


CombiMatrix, an operating division of Acacia Research, said it would work with Bonaventura Clotet, chief of the AIDS unit at the University Hospital Germans Trias i Pujol, to validate its HIV gene-targeted siRNA pools. According to Amit Kumar, president and CEO of CombiMatrix, the company's approach, which targets all of the genes in a virus, "may provide a more powerful therapy than conventional approaches, and it should make it difficult for the virus to develop resistance."


The HIV project is CombiMatrix's second collaboration based on its siRNA platform, following an earlier collaboration based on SARS with the National Institute of Allergy and Infectious Diseases and the US Army Medical Research Institute of Infectious Diseases.


The company said it is targeting a number of other viruses with the siRNA platform, including HIV type 2, West Nile virus, human papillomavirus type 16, human herpes 8 (Kaposi's sarcoma), smallpox (variola), influenza virus A, influenza virus B, hepatitis C, and leishmania RNA virus.

The Scan

Panel Recommends Pfizer-BioNTech Vaccine for Kids

CNN reports that the US Food and Drug Administration advisory panel has voted in favor of authorizing the Pfizer-BioNTech SARS-CoV-2 vaccine for children between 5 and 11 years old.

Sharing How to Make It

Merck had granted a royalty-free license for its COVID-19 treatment to the Medicines Patent Pool, according to the New York Times.

Bring it Back In

Bloomberg reports that a genetic analysis has tied a cluster of melioidosis cases in the US to a now-recalled aromatherapy spray.

Nucleic Acids Research Papers on SomaMutDB, VThunter, SCovid Databases

In Nucleic Acids Research this week: database of somatic mutations in normal tissue, viral receptor-related expression signatures, and more.