Skip to main content
Premium Trial:

Request an Annual Quote

Eric Green Hopes to Settle Finishing v. Draft Debate

BOSTON, Oct. 4 - How do you like your genomes: finished or draft?


In a talk here today at the Genome Sequencing and Analysis Conference, Eric Green of the National Human Genome Research Institute worked through one of the sequencing community's favorite debates. Green's research group, knee-deep in a study aimed at finally answering that question, plans to put together an abstract in time for the February Marco Island meeting, Green told GenomeWeb after his talk. Final results may come "within the next six to 12 months."


The study involves gathering datasets from a "pristinely finished" genome, a draft sequence, and one that falls between those extremes, Green said. The comparisons may yield definitive information on what standard is most efficient and cost-effective while being most useful to other scientists.


"The most important thing is that we're trying to do this systematically," he added.


At this point, Green will only venture a guess at the outcome of the debate. "My gut instinct is that there's no way we're going to finish every genome to the extent that we finish human," he said.


The study results will stand to have quite an impact on the sequencing community. Green pointed out in his talk that BAC libraries, a possible first step toward sequencing, are being prepared for many organisms that aren't on a priority genome list yet, such as rabbit, opossum, platypus, and bat.

The Scan

Not as High as Hoped

The Associated Press says initial results from a trial of CureVac's SARS-CoV-2 vaccine suggests low effectiveness in preventing COVID-19.

Finding Freshwater DNA

A new research project plans to use eDNA sampling to analyze freshwater rivers across the world, the Guardian reports.

Rise in Payments

Kaiser Health News investigates the rise of payments made by medical device companies to surgeons that could be in violation of anti-kickback laws.

Nature Papers Present Ginkgo Biloba Genome Assembly, Collection of Polygenic Indexes, More

In Nature this week: a nearly complete Ginkgo biloba genome assembly, polygenic indexes for dozens of phenotypes, and more.