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Epoch Wins SBIR Grant to Develop MGB High-Throughput Technology

NEW YORK, Dec. 11 - Epoch Biosciences has been awarded an $872,000 Small Business Innovation Research grant from the National Institutes of Health research grant, the company said on Tuesday.

 

The Phase II grant, entitled "Rapid Genotyping with Minor-Groove-Binder-Containing Probes," will span two years and will help Epoch develop a prototype kit for high-throughput DNA fingerprinting that uses probes containing Epoch's Minor Groove Binder technology.

 

According to the Bothell, Wash.-based molecular tools manufacturer, the MGB technology can enhance the ability of oligonucleotide probes to discriminate SNPs.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.