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EpiVax Wins $1M NIH SBIR Grant to Screen Genomes for Smallpox Vaccine

NEW YORK, Dec. 20 (GenomeWeb News) - EpiVax has won a $993,771 Phase I SBIR grant from the National Institutes of Health's National Institute of Allergy and Infectious Diseases to develop a smallpox vaccine, its second SBIR grant this year, the company said today.

 

EpiVax, a provider of protein and genome analysis services and vaccine candidates that is based in Providence, RI, plans to use the award to screen the genomes of variola, which causes smallpox, and vaccinia, which causes cowpox, for common epitopes that drive immunity.

 

In September, EpiVax received an $859,773 biodefense grant to develop a vaccine for Tularemia.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.