Skip to main content
Premium Trial:

Request an Annual Quote

Eli Lilly Takes Perpetual License to Entelos' DrugMatrix Database

NEW YORK (GenomeWeb News) – Entelos said today that Eli Lilly has purchased a perpetual license to its DrugMatrix toxicogenomics database.
 
Under the terms of the agreement, Lilly will make a one-time payment to Entelos for a perpetual license to the database and customized report services from the company’s ToxFx business, with the option for continued support.
 
Financial terms were not disclosed.
 
Entelos, a biosimulation firm that develops "virtual humans" to help predict drug response, picked up the DrugMatrix database in its acquisition of Iconix last August.
 
The database is a reference set of gene expression profiles for benchmark drugs and compounds that are linked to pharmacology, toxicology, and clinical pathology measurements. It currently includes profiles from more than 630 different compounds.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.