Skip to main content
Premium Trial:

Request an Annual Quote

Duke Team Sequences Genome of Pathogenic Plant Fungus

NEW YORK, March 4 (GenomeWeb News) - Researchers at the Duke Institute for Genome Sciences and Policy and the University of Basel have published the genome sequence of the pathogenic plant fungus Ashbya gossypii, the groups said today.


The organism, which infects agricultural crops such as cotton and citrus fruits, is believed to contain the smallest genome ever characterized among free-living eukaryotes, the researchers said.


A. gossypii's genome contains 9.2 million base pairs across seven chromosomes that encode 4,718 protein-coding genes, the researchers report in the March 4 Science Express, the online version of the Science. The fungus shares more than 90 percent of these genes with the yeast genome--with most occurring in a similar gene order, the scientists reported.

Led by Fred Dietrich, the researchers compared A. gossypii with yeast and found 300 instances of sequence inversion since the species diverged. The researchers also observed two copies of the majority of A. gossypii genes in the yeast genome, which they consider to be evidence that the evolution of S. cerevisiae included a whole genome duplication.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.