Skip to main content
Premium Trial:

Request an Annual Quote

DoubleTwist Signs on as Weizmann Institute s First GeneCards Licensee

NEW YORK, Jan 3 - Israel’s Weizmann Institute of Science has signed DoubleTwist as the first commercial licensee for its GeneCards Encyclopedia, a web-based interface that offers biomedical information about the structure and function of human genes, a source close to the project said Wednesday.

A spokesman from Yeda, the technology transfer arm of the Weizmann Institute, confirmed that a commercial entity is licensing GeneCards, although he declined to disclose the identity of the company or the financial details of the licensing agreement.

Catherine Collier, a DoubleTwist spokeswoman, declined to comment, saying the company was in a quiet period in the run-up to their planned initial public offering.

GeneCards began as an add-on to the Weizmann Institute’s Unified Database, a mapping database for all of the chromosomes. UDB is now one of 22 databases from which the GeneCards encyclopedia extracts data.

A typical GeneCards lists the official name of the gene, a list of synonyms, homologous genes in the mouse genome, the names of its protein products, and the UniGene cluster of sequences related to the gene. The card also lists disorders in which the gene appears to be involved, the coordinates of the gene, titles of related research articles, and medical applications based on knowledge about the gene.

There are currently 19,175 GeneCards in the system, more than doubling last January’s 9,445. The most recent release boosted the GeneCards count by 4,990.

Access to the main GeneCards site is available at http://bioinfo.weizmann.ac.il/cards . A Weizmann spokesperson declined to comment on how the commercial licensing deal would affect academic users’ access to the GeneCards website.

The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.