Skip to main content
Premium Trial:

Request an Annual Quote

Dharmacon Moves into Large-Scale Oligo Synthesis

NEW YORK, Dec. 5-Oligonucleotide developer Dharmacon said yesterday that it now offers large-scale, high-throughput RNA synthesis services.


The company says that its 5'-silyl-2'-ACE synthesis chemistry now allows it to deliver gram-sized amounts of oligos.


Anticipating growth in the synthetic RNA market, Dharmacon plans to soon be able to fulfill orders ranging from hundreds of milligrams to 100 grams, and hopes ultimately to deliver quantities up to a kilogram.

Interest in RNAi technology is driving the growth in the synthetic oligo market, the company said.

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.