Skip to main content
Premium Trial:

Request an Annual Quote

DeCode Awarded $24 Million by NIH to Study Genetics of Infectious Disease and Vaccine Response

NEW YORK, Oct. 8 (GenomeWeb News) - DeCode genetics announced today that it has been awarded a five-year, $23.9 million contract by the National Institute of Allergy and Infectious diseases to discover genetic factors associated with susceptibility to certain infectious diseases. The Raykjavik, Iceland-based company will also apply its population-based research approach to investigate genetic factors associated with vaccine response.

 

More specifically, the contract states that DeCode will conduct genome-wide scans in Icelandto search for key genes involved in susceptibility to tuberculosis; adverse reaction to smallpox vaccination; and susceptibility to influenza and certain bacterial infections, such as those that cause pneumonia and meningitis.

 

Following the identification of targets by DeCode, a team at the Universityof New Mexicoled by Rick Lyons will conduct functional validation studies on the targets. In addition, the NationalCenterfor Genome Resources, headed by Stephen Kingsmore, will design and maintain an internet-based Immune Response database that will enable investigators to query and visualize results of the project in the context of existing data on the genetics of immune response.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.