SAN FRANCISCO, May 30 - Steve Madden is looking for a job. After being laid off in January from now-defunct DoubleTwist, he has been doing the biotech version of pounding the pavement: networking at bioinformatics industry events and handing out resumes at job fairs.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.