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CST and AstraZeneca to Identify Phosphorylation Profiles in Pilot

NEW YORK, Jan. 10 (GenomeWeb News) - Cell Signaling Technology will expand a pilot study on phosphorylation profiles with AstraZeneca, the company said today.

 

As reported in Cell-Based Assay News  in June 2004, the pilot study will identify phosphorylation profiles and prospective biomarkers of kinase-targeted lead compounds.

 

CST's PhosphoScan proteomics technology identifies Phospho-Signatures in cells and disease tissues to enable the development of biomarker assays for target validation.

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.