By Matt Jones

NEW YORK (GenomeWeb News) – US President Barack Obama signed a bill last night that will keep the federal government operating for the next two months at fiscal-year 2010 spending levels, which could put in peril the White House's and Congress' proposed increases for biomedical research in the 2011 budget.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.