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CombiMatrix, University of Washington to Co-develop Array-Based Dx for Lymphoma

NEW YORK, Sept. 11 (GenomeWeb News) - CombiMatrix and the Universityof Washingtonplan to co-develop a microarray-based test for diagnosing lymphoma, the two groups said today.

A team of university researchers led by Daniel Sabath and Stephen Schmechel, at the Departments of Laboratory Medicine and Pathology in the Schoolof Medicine, claimed to have identified a subset of genes whose expression pattern can "distinguish the various lymphoma types." The goal of the collaboration, then, is to harness those data and develop array-based diagnostics that detect lymphomas and predict clinical outcome.

To help develop and commercialize a potential product, CombiMatrix has penned an agreement with RationalDiagnostics. Last year, Seattle-based RationalDiagnostics, which was co-founded by Sabath and Schmechel, signed a deal with the Universityof Washingtonand the WashingtonTechnologyCenterthat ultimately helped uncover ways of using microarrays to diagnose lymphoma.


Existing methods of diagnosing lymphoma, which are based on examining tissue biopsies for a small number of markers, are often inaccurate and offer physicians "limited information" about the expected course of a patient's cancer progression.

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