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CombiMatrix and IrsiCaixa Expand RNAi Research to Hepatitis C

NEW YORK, March 23 (GenomeWeb News) - Acacia Research's CombiMatrix unit and researchers at the IrsiCaixa Foundation in Spain have expanded their RNAi collaboration to include hepatitis C, Acacia said today.


Under the expanded agreement, scientists led by Bonaventura Clotet will screen pooled siRNA compounds provided by CombiMatrix for efficacy against the hepatitis C virus.


The IrsiCaixa researchers, based in Barcelona, Spain, have already been testing siRNA compounds from CombiMatrix on HIV since last year.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.