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Columbia University Awarded $11M NHGRI Grant for Genomics

NEW YORK, Sept. 23 (GenomeWeb News) - The NHGRI has awarded Columbia University an $11 million, three-year grant and designated the university a Center of Excellence in Genomic Science, the university said Monday.

 

The Columbia Center of Excellence, led by Jingyue Ju, an associate professor of chemical engineering and head of DNA sequencing and chemical biology at the Columbia Genome Center, will use the grant funds to develop new genomic methods for neurobiology research.

 

These include chip-based massively parallel genome sequencing, and nanoscopic DNA arrays for measurement of gene expression at the single-cell level, the university said.

 

"Massively parallel DNA sequencing promises to bring genetic analysis to the next level where we can envision, for example, the routine comparison of individual genome profiles, a key step for personalized medicine," Ju said in a statement.

 

The researchers will also use combinatorial fluorescence energy transfer tags and molecular beacons to monitor copies of genes in real-time, in studies of the model organism Aplysia on the role of genes in learning and memory.  Additional researchers will take part in the research under the grant.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.