Skip to main content
Premium Trial:

Request an Annual Quote

Ciphergen, Fulfilling Promise, Unveils PGx Biomarker Alliance With Bayer

NEW YORK, June 27 (GenomeWeb News) - Ciphergen Biosystems and Bayer Pharmaceuticals will try to identify biomarkers and develop an assay that may be used in Bayer clinical trials in cancer, the companies said today.

 

The announcement fulfills a promise Ciphergen made as early as last month in which it said it would unveil a diagnostic deal before the end of June. [For more on this angle, read the May 13 issue of ProteoMonitor].

 

Terms of the agreement call for Ciphergen to use its SELDI-TOF-MS platform to analyze patient samples from Phase II trials at its PharmaceuticalBiomarkerDiscoveryCenterlab in Malvern, Pa.

 

Ciphergen and Bayer will then co-analyze the resulting data to "identify biomarkers predictive of response" to an undisclosed Bayer compound currently in development.

 

Financial terms of the alliance were not disclosed, but Ciphergen said they include upfront fees and milestone payments.

 

The deal marks a significant milestone for Ciphergen, which has been hurt by slumping sales of its flagship SELDI platform in recent quarters. The company, which has had to undergo a restructuring to offset the sliding revenue, has said it expects biomarker alliances such as the one announced with Bayer to buttress the falling revenues.

 

CEO Bill Rich said in a May statement reporting the company's first-quarter earnings that he is "enthusiastic about the future growth of the company as we continue to address the emerging biomarker proteomics research, pharma and diagnostic markets." The Bayer pharmacogenomics deal is the first private-sector collaboration since the restructuring that Ciphergen disclosed.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.