Skip to main content
Premium Trial:

Request an Annual Quote

Children's National Medical Center to Use BioTrove Genotyping Platform in Studies

NEW YORK (GenomeWeb News) – Researchers at the Children’s National Medical Center in Washington, DC, will use BioTrove’s OpenArray SNP genotyping system to investigate genes associated with diseases such as diabetes and skeletal muscle hypertrophy, the company announced yesterday.
 
The center anticipates that the OpenArray system, which generates hundreds of thousands of SNP and qPCR data points each day, will expedite its determination of the genes influencing disease states in young patients.
 
“The high-throughput OpenArray system enables us to process samples in weeks instead of years, and its high accuracy helps conduct in-depth research without depleting our precious DNA samples,” said Eric Hoffman, director of Children’s National’s Research Center for Genetic Medicine.
 
The technology will be applied to several NIH-funded projects including a collaboration with Howard University researchers aimed at assessing pre-symptomatic risk factors for early onset type 2 diabetes in African-American children.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.