Five years ago, Genome Technology's cover story examined the rise of chemical genomics and profiled Chris Austin, who was kicking off a new small molecule screening initiative at NIH. Today, Austin is director of the NIH Chemical Genomics Center, which has established a successful track record through a model of partnering with experts in the community and designing assays critical for screening compounds. The center has built up a production-scale facility and capacity including some 400,000 compounds.

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