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Cepheid Shares Jump Nearly 18 Percent After FDA Clearance

Shares in Cepheid rose 17.8 percent for the five-day trading period ended Tuesday, following last week’s clearance by the US Food and Drug Administration of the firm’s meningitis molecular diagnostic assay. The test is Cepheid’s third molecular diagnostic product cleared by the FDA for sale in the US.
 
Shares in Affymetrix also continued their rise this week following a jury’s verdict last week that Illumina had infringed several Affy patents and awarded Affy $16.7 million in damages (see BioCommerce Week 3/14/2007). In addition, Bruker BioSciences hit a 52-week high of $10.54 on Tuesday before closing at $10.28.
 
Caliper Life Sciences led the two decliners in the BCW Index, with a drop of 6.5 percent for the tracking period.
 
Overall, the Index gained 2.9 percent for the week, outpacing the Nasdaq, which rose 2.5 percent, and the Nasdaq Biotech Index, which rose 1.2 percent. The Dow Jones Industrial Average rose 1.8 percent for the period.

 
 
BioCommerce Week Index of Diversified
Molecular Biology Tool Companies
Company
Ticker
Closing Price (March 20, 2007)
Starting Price Jan. (March 13, 2007)
% change
Affymetrix
AFFX
28.89
26.62
8.53
Agilent
A
32.06
31.67
1.23
Applied Biosystems
ABI
29.73
28.55
4.13
Beckman
BEC
65.58
64.98
0.92
Becton Dickinson
BDX
75.12
73.48
2.23
Bio-Rad
BIO
70.45
67.67
4.11
Bruker
BRKR
10.28
9.47
8.55
Caliper
CALP
5.36
5.73
-6.46
Cepheid
CPHD
10.01
8.5
17.76
Illumina
ILMN
29.63
28.86
2.67
Invitrogen
IVGN
62.72
61.01
2.80
Luminex
LMNX
14.75
14.07
4.83
Millipore
MIL
72.01
70.1
2.72
Molecular Devices
MDCC
35.46
35.38
0.23
PerkinElmer
PKI
23.56
23.19
1.60
Qiagen
QGEN
16.39
16.05
2.12
Sequenom
SQNM
3.99
4.05
-1.48
Sigma-Aldrich
SIAL
41.38
40.01
3.42
Stratagene
STGN
8.5
8.4
1.19
Thermo
TMO
46.38
44.94
3.20
Third Wave
TWTI
5.2
5.13
1.36
Waters
WAT
57.21
55.78
2.56
BCW Index Average  
33.85
32.89
2.90
The Scan

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.

Analysis of Endogenous Parvoviral Elements Found Within Animal Genomes

Researchers at PLOS Biology have examined the coevolution of endogenous parvoviral elements and animal genomes to gain insight into using the viruses as gene therapy vectors.

Saliva Testing Can Reveal Mosaic CNVs Important in Intellectual Disability

An Australian team has compared the yield of chromosomal microarray testing of both blood and saliva samples for syndromic intellectual disability in the European Journal of Human Genetics.

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.