The expansion "is in line with the terms of the original agreement between the two companies," Cellzome said.
Since September, Cellzome said it has mapped the protein networks of signaling pathways implicated in several therapeutic areas and has used this information to characterize various Novartis compounds. Under the terms of the expanded agreement, Cellzome said it will provide "more in-depth functional analyses of target candidates and signaling aspects of the disease pathways."
Novartis has made a "substantial equity investment" in Cellzome and will also contribute an undisclosed amount of research funding for two years with the option of extending the collaboration for a further two years, Cellzome said.
Terms of the agreement also include lead compound development options for both companies in exchange for licenses, milestone payments, and royalties.