Clarissa Desjardins’ serial startup career began, oddly enough, in the lab. “I made some discoveries during my PhD,” she says — she and her lab partner had discovered a particularly useful fluorescent reagent and decided to commercialize it. They founded Advanced Bioconcept Limited in 1992 and weren’t exactly prepared for what was to come: “Two recent science graduates trying to start a reagent business in peptides — it was a very big struggle,” she says.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.