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Cancer's "Moonshot"


Ron DePinho, the new president of the MD Anderson Cancer Center in Houston, hopes to cure five types of cancer — a feat that DePinho acknowledges is a "moonshot," reports The Economist. Which five cancers to tackle hasn't been decided yet, but The Economist says that the effort would only be possible because of the International Cancer Genome Consortium, which is working to thoroughly sequence the genomes of 50 cancer types. At MD Anderson, DePinho wants to "'industrialize' other aspects of biological research in the way that genetics has been pushed forward by high-throughput sequencing," The Economist says.

The Scan

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.

Seagull Microbiome Altered by Microplastic Exposure

The overall diversity and the composition at gut microbiome sites appear to coincide with microplastic exposure and ingestion in two wild bird species, according to a new Nature Ecology and Evolution study.

Study Traces Bladder Cancer Risk Contributors in Organ Transplant Recipients

In eLife, genome and transcriptome sequencing reveal mutation signatures, recurrent somatic mutations, and risky virus sequences in bladder cancers occurring in transplant recipients.

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.