In April of last year, we featured our fourth annual special issue devoted to cancer research. We highlighted the growing use of profiling miRNAs in tumors for possible use as biomarkers or in therapeutics. GWAS also held center stage, with scientists having found major associations in breast, prostate, and colon cancer in 2008. We featured work from NCI's Aaron Schetter, NIH's Stephen Chanock, and Brigham and Women's Hospital's David Sugarbaker, among others.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.