Skip to main content
Premium Trial:

Request an Annual Quote

Cancer Genomics at ICHG


Researchers at the International Congress of Human Genetics meeting in Montreal, Quebec, gave an update this morning on the status of some International Cancer Genome Consortium projects, particularly those on pancreatic, oral, and stomach cancer. New sequencing technologies have spurred the ICGC to sequence about 500 tumor varieties to try to find genomic, epigenomic, and transcriptomic changes that occur in those cancers. "It is relatively simple to think about doing cancer genomics," said session chair Tom Hudson from the Ontario Institute for Cancer Research. There are now 17,000 consenting donors for ICGC projects, and data from about 2,000 of those maybe found on the consortium's Web site.

Two speakers during the session touched on difficulties facing researchers in sequencing pancreatic cancer samples. One problem is that pancreatic tumor samples often include a fair amount of normal tissue, due to the characteristics of the tumor. However, the Broad Institute's Stacey Gabriel and her colleagues at The Cancer Genome Atlas showed that deep sequencing of such mixed samples could pick up pancreatic cancer mutations. Alternatively, John McPherson at OICR has used different enrichment approaches to increase the amount of usable tumor, also with some success.

The Scan

Not Immediately Told

The US National Institutes of Health tells lawmakers that one of its grantees did not immediately report that it had developed a more infectious coronavirus, Science says.

Seems Effective in Kids

The Associated Press reports that the Pfizer-BioNTech SARS-CoV-2 vaccine for children appears to be highly effective at preventing symptomatic disease.

Intelligence Warning on Bioeconomy Threats

US intelligence warns over China's focus on technologies and data related to the bioeconomy, the New York Times reports.

PLOS Papers on Campylobacteriosis Sources, Inherited Retinal Dystrophies, Liver Cancer Prognosis

In PLOS this week: approach to uncover source of Campylobacteriosis, genetic risk factors for inherited retinal dystrophies, and more.