NEW YORK, July 5 – In a typical sequence homology search, researchers looking to determine the function of a particular human gene try to match its sequence with a similar sequence in another, simpler organism’s genome, such as that of the mouse. Because many mouse genes are better understood, this provides clues as to what the human gene does. In many cases, however, when there is no direct relative in the mouse or other genome, this method breaks down. 

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