Skip to main content
Premium Trial:

Request an Annual Quote

Broad Institute Makes Genomics Data Viewer Public

NEW YORK (GenomeWeb News) – The Broad Institute of MIT and Harvard has created a genomics informatics tool that will allow researchers to visualize genomic information, and has made it publicly available for free, Broad said today.
The Integrative Genomics Viewer was developed to help researchers find effective ways to visualize the “vast amounts of diverse genomic data” that scientists are accumulating with “ever increasing speed,” according to the institute. It can incorporate multiple types of genomic data and allows researchers to view them at various levels of resolution.
"This new tool offers a Google Maps-like view of integrative genomic data," said Jill Mesirov, chief informatics officer and director of computational biology and bioinformatics at the institute.
Broad said it allows researchers a “street view” of proteins that make up the genome, and they can visualize layers of information about gene expression, sequence alterations, mutations, and other genomic details such as copy number variation, chromatin immunoprecipitation data, and epigenetic modifications.
"Other tools offer detailed, localized views of genomic data, and a few tools are equipped to provide a whole genome view," Broad software engineer Jim Robinson said in a statement. But, Robinson added, “IGV was designed to integrate both and to provide smooth zooming and panning across all resolution scales."
The IGV allows these kinds of data to be overlaid or superimposed to help determine how changes at one level can affect another.
There are various display options, and users may view data as a heat map, histogram, scatter plot, and other formats.
The IGV is available at Broad’s website

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.