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Brainy Avastin

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This post has been updated to clarify the study's findings. The updated Reuters story may be found here.

Avastin's effectiveness against breast cancer is still being debated, but Roche says there's now evidence to show that the drug, in combination with other treatments, has a significant effect on patients with glioblastoma, Reuters reports. Roche reported results of its phase III AVAglio study in which glioblastoma patients were treated with radiation, temozolomide and either Avastin or placebo, followed by temozolomide and either Avastin or placebo. According to Roche, the study shows Avastin improves progression-free survival of glioblastoma patients, Reuters says.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.