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Books of Interest

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Ontologies for Bioinformatics

By Kenneth Baclawski and Tianhua Niu

This textbook aims to provide an introductory yet thorough analysis of ontologies and languages for bioinformaticists, computer scientists, and other life science researchers faced with the task of sorting mountains of complex data. Divided into three parts, the book introduces readers to extant types of ontology, explains how ontologies are used and constructed, and contrasts Boolean with inductive modes of reasoning. The authors have included chapter summaries, exercises, answers, and a complete index to aid readers.

— JC


Publisher: The MIT Press

ISBN: 0262025914


Computational Systems Biology

Edited by Andres Kriete and Roland Eils

Eils and Kriete bring together an impressive roster of contributors in this technical guide to computational technologies and methods relating to systems biology. The authors present updates on modeling and simulating techniques, current research efforts on biochemical networks, and multi-scale modeling and analysis of biological systems.

 — JC


Publisher: Academic Press, Elsevier

ISBN: 012088786X


Structural and Evolutionary Genomics: Natural Selection in Genome Evolution

By Giorgio Bernardi

Author Bernardi points out in the preface that this book, which aims to review recent findings and present new data about structural and evolutionary genomics, focuses heavily on functional genomics as well. This book is for readers looking for an overview rather than a highly detailed examination of results: Bernardi covers 40 years worth of scientific discovery in about 400 pages.

— MS


Publisher: Elsevier

ISBN: 0444521364


Genetic Variance Detection: Technologies for Pharmacogenomics

Edited by Karl Hecker

Scientists including Mostafa Ronaghi and David Barker contributed chapters to this book, which discusses genetic variation detection tools such as sequencing, microarrays, mass spec, and others. The text, while quite technical, may be more appropriate for students, postdocs, or lab techs working hands-on with the technology than for scientists who are already familiar with the field.

— MS


Publisher: DNA Press

ISBN: 0974876550

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.