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BioPAL Awarded $100K SBIR Grant to Develop Diagnostics Based on Isotope-labeled Probes

NEW YORK, June 14 (GenomeWeb News) - BioPhysics Assay Laboratory (BioPAL) has been awarded a Phase I Small Business Innovation Research grant from the National Center for Research Resources to develop diagnostics based on stable isotope-labeled functional probes, the company said today.


BioPAL said the technology under development is "an automated accelerator-based neutron generation device" that will quantify the presence of stable isotope-labeled physiological probes in biological samples "without interference from the sample matrix."


BioPAL currently markets several stable isotope-labeled physiological probes, such as microspheres for blood flow studies and nanocolloids for cell labeling and tracking, but said that samples under investigation currently have to be returned to the firm to be assayed in a large, fixed neutron generator.


The SBIR grant will enable BioPAL to develop a compact device that could be installed at a researcher's institution, the company said.


The firm did not disclose the amount of the award, but an NIH database lists the company as a recipient for a $99,644 award entitled, "An Accelerator-Based Neutron Activation Device."


BioPAL said that it has been awarded more than $3 million in SBIR grants. The Worcester, Mass.-based company was founded in 1997.

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