Skip to main content
Premium Trial:

Request an Annual Quote

Biolog Expands E. Coli Research With Axiohelix, NARA Institute

NEW YORK, July 26 (GenomeWeb News) - Biolog, Axiohelix, and the NARA Institute have extended their collaboration to phenotype the E. coli genome, the partners said today.


The project, begun in November 2004, aims at developing complete profiles of cellular expression for every gene in organism's the genome. The process involves Biolog using its Phenotype Microarray technology to study the E. coli K-12 strain library developed by researchers at Keio and the Nara Institute, both based in Japan.


This collection contains strains for which each gene in the genome has been knocked-out. Last year, Biolog began generating 2,000 phenotypic responses for each gene knock-out in the genome. The company said it expects to expand this analysis in 2006 to include the entire E. coli genome.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.