The April 2006 cover story looked at the state of high-throughput imaging as the next great discovery tool in systems biology. The story featured leading vendors and institutes, including the Whitehead Institute at MIT, Cellomics, and GE Healthcare’s bioscience unit. Advances continue — with an increasing emphasis on live cell imaging, speed and sensitivity are becoming most important.

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Two new Reproducibility Project: Cancer Biology studies have largely reproduced the original findings, ScienceInsider reports.

DNA fingerprinting could catch some sample mix-ups at pathology labs, the New York Times says.

A Maryland police department has turned to DNA phenotyping to develop a suspect sketch, WJLA reports.

In Cell this week: DNA methylation and T cell exhaustion, longevity in C. elegans, and more.