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Benchmarking the Industry: Introducing the Genome Technology Index


Of the 26 companies that make up the Genome Technology Index, fully half were not public a year ago. At our editorial closing another dozen genome technology IPOs were in the pipeline.

We think an industry this dynamic deserves its own benchmark. So we’ve created one.

What kinds of companies constitute the GTI? In a field characterized by fast-changing technology and ever-adapting strategies, it would be premature to get overly explicit. Especially because many are hedging their bets by pursuing multiple business models.

Suffice it to say, we have three general criteria. First, a GTI company should be chiefly concerned with genomics: what Wall Street types would call a “pure play.” Second, it should be primarily in the business of developing technology ¯ data, software, equipment, consumables, services ¯ as opposed to developing, say, drugs or diagnostics. Finally, a GTI company should be pursuing a broad, commercial market for its technology rather than, for example, working with a small number of exclusive collaborators.

So who’s in the club? Have a look, and let us know what you think: [email protected]

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.