Skip to main content
Premium Trial:

Request an Annual Quote

Baylor Acquiring Six ABI SOLiD Systems for 1000 Genomes Project

NEW YORK (GenomeWeb News) – Baylor College of Medicine’s Human Genome Sequencing Center announced today that it will use Applied Biosystems’ high-throughput SOLiD sequencing systems during the pilot phase of the 1000 Genomes Project.
The Baylor HGSC will acquire six SOLiD systems for the first phase of the project, during which scientists there will try to determine the best method for sequencing 1,000 human genomes. During the pilot stage of the project, the HGSC plans to get significant sequence coverage of 24 human genomes along with deeper coverage of one human genome. With the systems, the HGSC expects to generate roughly 200 billion bases of sequence in the next four months.
The 1000 Genomes Project is intended to find clues about human genetic variation, which could provide insights into conditions such as cancer, diabetes, and heart disease, as well as individual differences in treatment responses. The HGSC also hopes to determine the depth of coverage needed to fully understand sequence variations (including SNPs, copy number variations, insertions, and deletions) between individuals. To do this, researchers must generate sequence data quickly and accurately — and at sufficient depth coverage.
In a statement, HGSC Director Richard Gibbs noted that the SOLiD system was selected for its ability to produce 25- to 50-base pair data at very high densities. The center reportedly selected the SOLiD system after doing experiments to compare it with competing short-read platforms for sequencing microbial and mammalian genomes.
The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.